Nanocomposites-based electrochemical aptasensor for dimethyl methylphosphonate (DMMP) detection

The initial goal of this work was to synthesize polypyrrole nanoparticles (PPy NPs) and PFFs nanocomposite as sensing material, placed on a screen-printed carbon electrode (SPCE) and used as aptasensor in detecting dimethyl methylphosphonate (DMMP). The aptansensor constructed after the optimization of sonication of PPy NPs and PFFs were optimized in two ways: aptamer concentration an incubation period. Electrochemical measurement involving cyclic voltammetry (CV) analysis attested the improvement concerning the sensitivity of the modified SPCE using PPY NPs and PFFs and the selectivity therof using different analytes including DMMP were determined using differential pulse voltammetry (DPV). The PPy NPs and PFF both showed significant decrease in the oxidation peak current with the presence various concentration of DMMP and various incubated duration, signifying the sensitivity of the modified SPCE.