Pojol, Fellyzra Elvya and Mohamat Yusuff, Soleha and Jamari, Nor Laili-Azua and Zulkifli, Nur Athitrah and Osman, Mohd Junaedy and Abd Rashid, Jahwarhar Izuan and Ong, Keat Khim and Fitruanto, Anwar and Jamal, Siti Hasnawati and Wan Yunus, Wan Md Zin and Teoh, Chin Chuang (2022) Design and development of aptamer-gold nanopartiele for colorimetric detection of methylphosphonic acid. In: 31st Regional Conference on Solid State Science and Technology (RCSSST2022), 6-8 September 2022, Hotel Perdana, Kota Bharu, Kelantan. (Submitted)
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Abstract
Response surface methodology (RSM) based on face-centered central composite design (FCCCD) was applied to optimize the methylphosphonic acid (MPA) detection using DNA aptamer-citrate capped-gold nanoparticles (DNA aptamer-cit-AuNPs). Images of the color change of the solution were captured and further processed to red (R), green (G) and blue (B) values. Three parameters: cit-AuNPs concentration (Xi) , DNA aptamer concentration (X2) and incubation period (X3) were investigated. Analysis of variance (ANOVA) was used to determine the significant factors affecting the detection. Both predicted and experimental responses show good agreement at 95% confidence level. Hence, this method could be implemented for on-site MP A detection.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Uncontrolled Keywords: | methylphosphonic acid, cit-AuNPs, DNA aptamer |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology T Technology > TP Chemical technology |
| Divisions: | Centre For Graduate Studies |
| Depositing User: | Mr Shahrim Daud |
| Date Deposited: | 06 Apr 2023 07:42 |
| Last Modified: | 06 Apr 2023 07:42 |
| URI: | http://ir.upnm.edu.my/id/eprint/217 |
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